Fatigue/ Chronic Fatigue Syndrome/ Fibromyalgia

Why haven’t doctors helped me?

“There’s nothing wrong with you.” “It’s all in your head.” Or so doctors have told you. Meanwhile, you can’t get out of bed in the morning, no matter how much you sleep. Your joints and muscles hurt, and you can’t think straight. Sound familiar?

When faced with patients suffering from chronic fatigue syndrome (CFS) or fibromyalgia, doctors are often at a loss. In a poorly-informed attempt to relieve symptoms, they might prescribe antidepressants, muscle relaxants, pain pills, or sleep medications. None of these will resolve the condition and side effects may make you feel worse.

Lack of standardized testing for CFS and fibromyalgia is one problem. And another is this: Even when a correct diagnosis is made, there is no one-size-fits-all treatment.

You can get your life back!

These diseases are a blend of malfunctions in the body, much like an orchestra playing so terribly out of tune that the audience begs for ear plugs. To be effective, the treatment must identify which instruments are off-key—the unique situation of each patient—and correct them. We call this a multi-system approach, and it works.

Thousands of patients have improved

At Holtorf Medical Group, we conducted a study with 500 consecutive patients who were treated with our multi-system protocol. It was published in the Journal of Chronic Fatigue Syndrome. Previously, these patients had seen an average of 7.2 other doctors for CFS or fibromyalgia without significant improvement.

In contrast, by our patients’ fourth visit, their average energy level and sense of well-being had doubled. And 94 percent had overall improvement in their symptoms. More than 5,000 other patients, treated by more than 40 other doctors trained in the same protocol, have also experienced significant relief.

What are the symptoms of CFS and fibromyalgia?

Symptoms of CFS and fibromyalgia can be very similar, or even identical, and up to 70 percent of patients suffer from both conditions. Symptoms include:

  • Fatigue that doesn’t go away with sleep
  • Difficulty getting restful sleep
  • Pain, stiffness, or tender spots in muscles and/or joints
  • Headaches
  • Sore throat
  • Flu-like feeling
  • Getting tired very easily after minor exertion
  • Weight gain
  • Digestive problems
  • Mental fog or confusion
  • Poor concentration

Is it one disease, or two?

Technically, the difference is this: CFS is a malfunction of the pituitary, a pea-sized gland at the base of the skull, which regulates all our hormones. In fibromyalgia, the malfunction is in the hypothalamus, a part of the brain that lies just above the pituitary. The hypothalamus also plays a key role in regulating hormones, as well as the nervous system.

Underlying causes

The pituitary and hypothalamus work together and whether one or both are malfunctioning, they share the same underlying problems. Although each situation is unique, patients improve when these common factors are checked for and addressed as needed:

Malfunctioning mitochondria

Each cell in our bodies has tiny components called mitochondria, whose job it is to generate energy. They are often called the “furnaces” within each cell. The hypothalamus and pituitary are especially sensitive to any malfunction and fatigue is one of the symptoms.

Mitochondria can be poisoned by environmental toxins; pesticides; chronic bacterial, viral and fungal infections; and nutritional and hormone deficiencies. These can be identified and corrected.

Hormonal deficiencies

Thyroid and cortisol deficiencies are the most common ones. Cortisol, the fight-or-flight hormone triggered by stress, becomes depleted because the body is no longer able to produce sufficient amounts. Exhaustion is a symptom.

Thyroid hormone is depleted by exposure to toxins and by malfunctions in the hypothalamus and/or pituitary. You can learn more about thyroid here.

Safe forms of these hormones can be prescribed, based on a patient’s needs. Tests may also reveal other hormonal deficiencies.


Infections can either trigger or contribute to CFS or fibromyalgia. These may include viruses such as Epstein Barr or herpes, or bacterial infections, including Lyme disease. They can be identified and treated.

Other contributing conditions

In response to a chronic infection, the immune system can cause a special type of clotting disorder called “coagulation.” Instead of producing blood clots, it generates a coating on the insides of blood vessels. This coating interferes with delivery of oxygen and nutrients to all parts of the body, contributing to chronic fatigue. It can be treated with anti-coagulants.

Neurotoxins, such as mercury or other metals lodged in the brain, can also contribute to CFS and fibromyalgia. If suspected, these can be detected by brain scans and treated with chelating agents to eliminate the toxins.

The key to effective treatment

Doctors who are trained in our CFS and fibromyalgia protocol look for and treat all the factors underlying these diseases. This approach relieves symptoms while enabling healing.

Every aspect of our multi-system approach is supported by clinical research. And, thousands of patients have experienced the results.

To learn more about our treatment, click here to read about our outcomes as published in peer-reviewed medical journals.