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Ozone Q+A: What Patients Want to Know

Holtorf Medical Group

What is ozone therapy?

Ozone is a three-oxygen molecule (O3) that maintains antimicrobial and anti-inflammatory properties. Ozone therapy is an oxidative therapy that can be used to treat and manage conditions that cause inflammation or infections, including Lyme disease and other chronic illnesses.

In what ways can you use ozone for therapy?

Ozone has been shown to have healing, detoxifying, and anti-inflammatory qualities. Forms of ozone therapy can include blood (IV therapy), rectal insufflation, ear ozone, and others.

Intravenous ozone therapy is achieved through a process known as autohemotherapy by separating and oxygenating the patient’s blood. First, blood is drained, then it is exposed to a precise amount of ozone and finally, re-injected into the body via a catheter. Although this process may sound intimidating, the experience does not differ much from other IV therapies.

The use of Ozone seems to be highly debated online. Why?

Ozone has been used for decades to treat a host of medical conditions and infections. The confusion surrounding ozone therapy may be due to the fact that ozone is a gas. However, ozone therapy is extremely safe when performed by a licensed medical professional.

In fact, one of the reasons IV ozone is great for those suffering from chronic illnesses is, unlike many other treatments and medications, it has little to no side effects with a high safety profile.

What are the side effects of an ozone IV?

A common side effect from IV ozone therapy is a Herxheimer Reaction. While the body is cleansing toxins and waste, patients may temporarily experience flu-like symptoms before experiencing the positive effects of ozone.

Can healthy people use ozone IVs for health maintenance?

IV ozone therapy can have all the same benefits for “healthy” people as they do for those with chronic health conditions. Benefits can include:

  • Elimination or reduction in symptoms associated with pathogens such as viruses, bacteria, and parasites through stimulation of lymphocytes.
  • Improvement in blood and oxygen circulation.
  • Improvement of immune function.
  • Detoxification by neutralizing toxins processed in the liver and kidneys.

How does ozone affect gut bacteria? Can it cause an imbalance?

Ozone helps remove inflammation and kill harmful gut bacteria while allowing healthy microflora to flourish. However, IV ozone is not the most effective treatment method if gut health is your primary concern. Rectal insufflation is a form of ozone therapy that can benefit GI-related concerns. This form of ozone therapy consists of the introduction of pure, medical-grade ozone directly into the colon, allowing it to be quickly absorbed by the walls of the colon. This specific type of ozone treatment is able to:

  • Eliminate toxins from the gut (and thus, the rest of the body)
  • Restore the gut microbiome to an optimal state
  • Kill unwanted bacteria, parasites, viruses, and yeast in the gut

If you are interested in benefiting from ozone treatment, contact us today!


Holtorf Medical GroupThe Holtorf Medical Group specializes in optimizing quality of life and being medical detectives to uncover the underlying cause of symptoms, rather than just prescribing medications to cover-up the symptoms. We are experts in natural, prescription bioidentical hormone replacement and optimization, complex endocrine dysfunction, fibromyalgia, chronic fatigue syndrome and Lyme disease. We’ve dedicated our practice to providing you the best in evidenced-based, integrative medicine that’s not only safe and effective, but provides measurable results.


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