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Supplements To Support Immune Health

Holtorf Medical Group

Every day we are exposed to and come into contact with an incredibly large number of harmful pathogens and other disease-carrying substances. Fortunately, the body is protected by its immune system, which provides exceptional defense against agents of illness. However, in our current health climate, there is increased concern regarding the spread and prevention of disease. You can take an active role in preventing sickness and protecting your health by supporting immune function through supplementation.

The Basics of Immune Function

The immune system is tasked with protecting the body from any disease-inducing substances known as pathogens. Poor immune function is associated with a greater occurrence of illness, chronic disease, and even chronic health issues such as diabetes and cancer. This is in part because pathogens can more easily infect the body if the immune system is not functioning properly. Fortunately, it is possible to improve immune function and reduce the risk of serious illness through appropriate supplementation.

An Introduction to Supplementation Dietary supplements are products composed of various nutrients, vitamins, minerals, or other health-supporting substances. Depending on its specific formulation, a supplement may provide a range of health benefits.

Many people employ vitamins and supplements specifically to support and empower their immune system. Doing so can help protect against various forms of disease ranging from the common cold to more serious viruses.

A few vitamins and supplements known for their immune-boosting properties include:

  • Vitamin C

  • Zinc

  • Arabinogalactan

  • Probiotics

  • Beta-Glucan

  • Vitamin A

  • Vitamin D

  • Vitamin E

  • Miatake Mushroom Extract

Using a number of these beneficial substances, HoltraCeuticals formulated a natural immune-boosting supplement, ImmunoStim.

What is ImmunoStim?

ImmunoStim is a supplemental product produced by HoltraCeuticals’ designed to improve immune function. Specifically, ImmunoStim supports illness prevention and intervention by encouraging the elimination of disease-inducing pathogens. ImmunoStim is particularly beneficial for those with poor immune function, a weakened immune system, or individuals who want to proactively protect themselves against viruses.

How Does ImmunoStim Work?

ImmunoStim supports various factors of immune function including but not limited to the activation of T-cells, immune-supporting cytokines, and anti-inflammatory cytokines. But the most impressive quality of ImmunoStim is that it encourages the production and mobilization of Natural Killer (NK) cells.

NK cells are essential for the elimination of disease-causing pathogens. This makes them one of the body’s primary agents in combating a wide range of illnesses including chronic conditions. Studies show that increasing the number and activity level of NK cells helps the immune system more effectively respond to threats and eliminate already established pathogens. Some research suggests that increasing NK cell values may even improve the body’s defenses against novel viruses.

What’s in ImmunoStim?

The source of ImmunoStim’s impressive benefits is its exceptional immune-supporting ingredients. Powerful substances found in ImmunoStim such as beta-glucan, olive leaf extract, maitake mushroom extract, and arabinogalactan provide impressive immune support.


Beta-glucan is a naturally occurring substance with notable immunological properties. Until recently, it was thought that oral supplementation with beta-glucan was ineffective. However, we now know that oral delivery can indeed provide many impressive benefits. These include improved anti-inflammatory and anti-bacterial activity, better immune modulation, and more efficient elimination of colds, flu, and other viruses.

Supplementation with beta-glucan is widely considered to be safe. However, there is some concern that beta-glucan may lower blood sugar meaning that hypoglycemic individuals or those taking medications to reduce blood sugar may want to avoid it.

Olive Leaf Extract

Throughout history, olives and olive oil have been utilized for their many presumed health benefits. In the modern era, science has confirmed that olives, specifically olive leaf extract, provides notable immune support.

Studies show that multiple bioactive compounds contained in olive leaves have a positive influence on various factors of immunity. Some of these compounds include secoiridoids, flavonoids, and triterpenes, all of which help combat a wide range of conditions ranging from the common cold to serious viral infections. In addition to combating illness, supplementing with olive leaf extract may also improve antioxidant activity, reduce blood pressure, and better regulate inflammation.

Maitake Mushroom Extract

Studies show that mushrooms support many factors of immunity. However, maitake mushrooms have proven to be particularly potent regarding immune function. Maitake contains multiple substances known to help the immune system more effectively respond to viruses, toxins, and other pathogens. Maitakes also contain bioactive molecules that provide anti-inflammatory, antiviral, and antioxidant benefits.

Importantly, studies show that supplementing with maitake increases the production of B and T lymphocytes. These compounds help prevent free radical damage and minimize the impact of already established diseases.


Arabinogalactan is found naturally in many plants recognized for their immune-supporting properties. Studies show that supplementing with arabinogalactan improves NK cell activity, which as mentioned previously are essential for healthy immune activity.

Taking arabinogalactan has also been shown to support the function of macrophages. Macrophages are large cells mobilized to consume or eliminate harmful particles including bacteria, fungi, parasites, and viruses.

Research also suggests that increasing values of arabinogalactan may have a positive effect on gut health. Because most of the immune system is located in the gut, supporting function in this way may result in improved immune activity.

Supplementing Safely

Although supplements can provide impressive benefits, it is important to know that not all supplements are created equal. Some products include low-quality ingredients that provide no meaningful value and may even be a detriment to your health. Therefore, when supplementing, it is essential to only use the best quality products. You can be assured that you are getting only the highest quality ingredients when taking HoltraCeuticals’ ImmunoStim.

Improve Your Immune System and Overall Well-Being

As the risk of illness increases, we must take additional steps to protect ourselves. Supporting the immune system through supplementation is an easy and effective way to bolster your body’s defenses against a wide range of diseases including viruses. You can take an active role in protecting your health by supplementing with HoltraCeuticals’ ImmunoStim. The powerful collection of natural ingredients supports multiple important factors of immunity that help prevent illness and alleviate already existing sickness.


  1. Stier, Heike et al. “Immune-modulatory effects of dietary Yeast Beta-1,3/1,6-D-glucan.Nutrition journal vol. 13 38. 28 Apr. 2014.
  2. D. Markin, L. Duek, I. Berdicevsky. “In vitro antimicrobial activity of olive leaves. Antimikrobielle Wirksamkeit von Olivenblättern in vitro.DOI: 10.1046/j.1439-0507.2003.00859.x
  3. Liu, Yanhong et al. “Assessment of the Antimicrobial Activity of Olive Leaf Extract Against Foodborne Bacterial Pathogens.Frontiers in microbiology vol. 8 113. 2 Feb. 2017.
  4. Sylvia Lee-Huang et al. “Anti-HIV activity of olive leaf extract (OLE) and modulation of host cell gene expression by HIV-1 infection and OLE treatment.Biochemical and Biophysical Research Communications. Volume 307, Issue 4, 8 August 2003, Pages 1029-1037.
  5. Somerville, Vaughan et al. “The Effect of Olive Leaf Extract on Upper Respiratory Illness in High School Athletes: A Randomised Control Trial.Nutrients vol. 11,2 358. 9 Feb. 2019.
  6. Gregory S. Kelly, N.D. “Larch Arabinogalactan: Clinical Relevance of a Novel Immune-Enhancing Polysaccharide.Foundational Medicine Review
  7. Dion, Carine et al. “Does larch arabinogalactan enhance immune function? A review of mechanistic and clinical trials.Nutrition & metabolism vol. 13 28. 12 Apr. 2016.
  8. Guggenheim, Alena G et al. “Immune Modulation From Five Major Mushrooms: Application to Integrative Oncology.Integrative medicine (Encinitas, Calif.) vol. 13,1 (2014): 32-44.
  9. Vetvicka, Vaclav, and Jana Vetvickova. “Immune-enhancing effects of Maitake (Grifola frondosa) and Shiitake (Lentinula edodes) extracts.Annals of translational medicine vol. 2,2 (2014): 14.

Holtorf Medical GroupThe Holtorf Medical Group specializes in optimizing quality of life and being medical detectives to uncover the underlying cause of symptoms, rather than just prescribing medications to cover-up the symptoms. We are experts in natural, prescription bioidentical hormone replacement and optimization, complex endocrine dysfunction, fibromyalgia, chronic fatigue syndrome and Lyme disease. We’ve dedicated our practice to providing you the best in evidenced-based, integrative medicine that’s not only safe and effective, but provides measurable results.

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